Human Perforin ELISpot Set, 5 x 96-well (plates not included)
CNY 8,063.00
货期*
6周
规格
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Specifications
Product Data | |
Description | Human Perforin ELISpot Set, 5 x 96-well (plates not included) |
Size | 5 x 96 wells (plates not included) |
Format | 5 x 96-well (plates not included) |
Assay Type | Enzyme-Linked ImmunoSpot (ELISpot) |
Assay Length | 3h after cell stimulation |
Signal | Colorimetric |
Specificity | Recognizes natural human Perforin |
Components | ELISpot Sets include capture and detection antibodies, Streptavidin - Alkaline Phosphatase conjugated, BSA, BCIP/NTB, and blocking reagent. |
Background | The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008] |
Gene Symbol | PRF1 |
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