Human IL-5 ELISpot Set, 5 x 96-well (non-sterile plates)

Specifications

Product Data
Description	Human IL-5 ELISpot Set, 5 x 96-well (non-sterile plates)
Size	5 x 96 wells (non-sterile plates)
Format	5 x 96-well (non-sterile plates)
Assay Type	Enzyme-Linked ImmunoSpot (ELISpot)
Assay Length	3h after cell stimulation
Signal	Colorimetric
Specificity	Recognizes both natural and recombinant human IL-5
Cross Reactivity	No cross reactivity with other human cytokines
Components	ELISpot Sets include capture and detection antibodies, Streptavidin - Alkaline Phosphatase conjugated, BSA, BCIP/NTB, blocking reagent, and 5 non-sterile plates.
Background	This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. [provided by RefSeq, Jul 2013]
Gene Symbol	IL5

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