Human CD126 ELISA Kit, 1 x 48-well (pre-coated)

Specifications

Product Data
Description	Human CD126 ELISA Kit, 1 x 48-well (pre-coated)
Size	1 x 48 wells (pre-coated)
Format	1 x 48-well (pre-coated)
Assay Type	Solid Phase Sandwich ELISA
Assay Length	1h40min
Signal	Colorimetric
Curve Range	31.25-1000 pg/ml
Sample Type	Serum, Plasma, Cell culture supernatant
Sample Volume	100 µl
Specificity	Recognizes both natural and recombinant human soluble IL-6R
Sensitivity	5 pg/ml
Cross Reactivity	No cross reactivity with other human soluble receptors. No interference with neither soluble gp130 nor IL-6.
Interference	No significant interference observed with available related molecules.
Components	ELISA Kits include pre-coated strip plates, biotinylated secondary antibody, standards, controls (where applicable), buffers, streptavidin-HRP, TMB, stop reagents, and a detailed procedure.
Background	This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9. [provided by RefSeq, May 2011]
Gene Symbol	IL6R
Standard Curve	Representative Standard Curve

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