Human Cancer Antigen CA 15-3 ELISA kit

Specifications

Product Data
Description	Human Cancer Antigen CA 15-3 ELISA kit
Size	1 x 96 wells
Format	96-well strip plate
Assay Type	Solid Phase Sandwich ELISA
Assay Length	4 hours
Signal	Colorimetric
Curve Range	Standard Curve Range: 0-240 U/ml
Sample Type	Human serum
Sample Volume	20 ul
Specificity	This kit is used for quantitative detection of human CA15-3
Sensitivity	Minimum Sensitivity: 5.0 U/ml
Reactivity	Human
Cross Reactivity	N/A
Interference	No significant interference observed with available related molecules.
Background	This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011]
Gene Symbol	MUC1
Standard Curve	Representative standard curve for CA15-3 ELISA

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