SP1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB1:500, IHC 1:100 to 1:200
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Full length protein
Formulation	PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification	Purified from the immunized serum by affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	86 kDa
Gene Name	Sp1 transcription factor
Database Link	Entrez Gene 6667 Human UniProt ID P08047
Background	The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes; including cell differentiation; cell growth; apoptosis; immune responses; response to DNA damage; and chromatin remodeling. Post-translational modifications such as phosphorylation; acetylation; glycosylation; and proteolytic processing significantly affect the activity of this protein; which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene.
Reference Data

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