Integrin beta 4 (ITGB4) Rabbit Polyclonal Antibody

CAT#: TA890131S

Rabbit Polyclonal anti-ITGB4 Antibody

Size: 30 ul 100 ul



 

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CNY 800.00


货期*
现货

规格
    • 30 ul

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经常一起买 (3)
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Purified recombinant protein of Homo sapiens integrin, beta 4 (ITGB4), transcript variant 1, 20 µg
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Transient overexpression lysate of integrin, beta 4 (ITGB4), transcript variant 1
    • 100 ug

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Specifications

Product Data
Applications WB
Recommend Dilution WB: 1:500~2000
Reactivity Human, Rat, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen Recombinant protein of human ITGB4
Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration 2.87 mg/ml
Purification Purified from the immunized serum by affinity chromatography (Protein A/G)
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 200.72 kDa
Gene Name integrin subunit beta 4
Background Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms CD104; GP150
Reference Data
Protein Families Druggable Genome
Protein Pathways Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Regulation of actin cytoskeleton
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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