SLP76 (LCP2) Mouse Monoclonal Antibody [Clone ID: OTI8D5]

Specifications

Product Data
Clone Name	OTI8D5
Applications	WB
Recommend Dilution	WB 1:500
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment of Human LCP2 (NP_005556) produced in Ecoli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws.
Predicted Protein Size	60.2 kDa
Gene Name	lymphocyte cytosolic protein 2
Database Link	NP_005556 Entrez Gene 16822 MouseEntrez Gene 3937 Human UniProt ID Q13094
Background	This gene encodes an adapter protein that acts as a substrate of the T cell antigen receptor (TCR)-activated protein tyrosine kinase pathway. The encoded protein associates with growth factor receptor bound protein 2, and is thought to play a role TCR-mediated intracellular signal transduction. A similar protein in mouse plays a role in normal T-cell development and activation. Mice lacking this gene show subcutaneous and intraperitoneal fetal hemorrhaging, dysfunctional platelets and impaired viability. [provided by RefSeq, Nov 2016]
Synonyms	IMD81; SLP-76; SLP76
Reference Data
Protein Pathways	Fc epsilon RI signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway

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