Drebrin (DBN1) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1B8]

Specifications

Product Data
Clone Name	OTI1B8
Applications	WB
Recommend Dilution	WB 1:2000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 2-240 of human DBN1 (NP_004386) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	HRP
Storage Condition	Store at -20°C as received.
Predicted Protein Size	71.3 kDa
Gene Name	drebrin 1
Database Link	NP_004386 Entrez Gene 56320 MouseEntrez Gene 1627 Human UniProt ID Q16643
Background	The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Synonyms	D0S117E
Reference Data

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