WDR77 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI5E9]

Specifications

Product Data
Clone Name	OTI5E9
Applications	WB
Recommend Dilution	WB 1:500~2000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 1-250 of human WDR77 (NP_077007) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Gene Name	WD repeat domain 77
Database Link	NP_077007 Entrez Gene 70465 MouseEntrez Gene 310769 RatEntrez Gene 79084 Human UniProt ID Q9BQA1
Background	WDR77 is a component of the 20S PRMT5 (MIM 604045)-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins (see MIM 601061). This modification targets Sm proteins to the survival of motor neurons (SMN) complex (see MIM 600354) for assembly into small nuclear ribonucleoprotein core particles (Friesen et al., 2002 [PubMed 11756452]). [supplied by OMIM, Mar 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC016946.1, BC001679.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support ERS025081, ERS025082 [ECO:0000350] ##Evidence-Data-END##
Synonyms	HKMT1069; MEP-50; MEP50; Nbla10071; p44; p44/Mep50
Reference Data
Protein Families	Stem cell - Pluripotency

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