TRIB3 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI2D11]

Specifications

Product Data
Clone Name	OTI2D11
Applications	IHC
Recommend Dilution	IHC 1:150
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 1-200 of human TRIB3(NP_066981) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	HRP
Storage Condition	Store at -20°C as received.
Predicted Protein Size	39.4 kDa
Gene Name	tribbles pseudokinase 3
Database Link	NP_066981 Entrez Gene 57761 Human UniProt ID Q96RU7
Background	The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants. [provided by RefSeq, Jul 2014]
Synonyms	C20orf97; NIPK; SINK; SKIP3; TRB3
Reference Data
Protein Families	Druggable Genome, Protein Kinase, Transcription Factors

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