PISD Mouse Monoclonal Antibody [Clone ID: OTI3B11]

Specifications

Product Data
Clone Name	OTI3B11
Applications	IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 80-340 of human PISD(NP_055153) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	phosphatidylserine decarboxylase
Database Link	NP_055153 Entrez Gene 320951 MouseEntrez Gene 681361 RatEntrez Gene 23761 Human UniProt ID Q9UG56
Background	Phosphatidylserine decarboxylases (PSDs; EC 4.1.1.65) catalyze the formation of phosphatidylethanolamine (PE) by decarboxylation of phosphatidylserine (PS). Type I PSDs, such as PISD, are targeted to the inner mitochondrial membrane by an N-terminal targeting sequence. PISD also contains a conserved LGST motif that functions as an autocatalytic cleavage site where the proenzyme is split into mature alpha and beta subunits (Schuiki and Daum, 2009 [PubMed 19165886]). [supplied by OMIM, Jul 2010]
Synonyms	DJ858B16; dJ858B16.2; PSD; PSDC; PSSC
Reference Data
Protein Pathways	Glycerophospholipid metabolism, Metabolic pathways

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