Rb (RB1) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI9E10]
CAT#: TA805630AM
RB1 mouse monoclonal antibody, clone OTI9E10 (formerly 9E10), Biotinylated
Conjugation: Unconjugated HRP
View other "OTI9E10" antibodies (4)
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CNY 3,990.00
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Clone Name | OTI9E10 |
Applications | WB |
Recommend Dilution | WB 1:2000 |
Reactivity | Human, Mouse, Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 309-590 of human RB1(NP_000312) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.5 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Biotin |
Storage Condition | Store at -20°C as received. |
Gene Name | RB transcriptional corepressor 1 |
Database Link | |
Background | The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008] |
Synonyms | OSRC; p105-Rb; pp110; PPP1R130; pRb; RB |
Reference Data | |
Protein Families | Druggable Genome, Transcription Factors |
Protein Pathways | Bladder cancer, Cell cycle, Chronic myeloid leukemia, Glioma, Melanoma, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Prostate cancer, Small cell lung cancer |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF805630 | Carrier-free (BSA/glycerol-free) RB1 mouse monoclonal antibody, clone OTI9E10 (formerly 9E10) |
CNY 3,999.00 |
|
TA805630 | RB1 mouse monoclonal antibody, clone OTI9E10 (formerly 9E10) |
CNY 1,999.00 |
|
TA805630BM | RB1 mouse monoclonal antibody, clone OTI9E10 (formerly 9E10), HRP conjugated |
CNY 3,990.00 |
|
TA805630S | RB1 mouse monoclonal antibody, clone OTI9E10 (formerly 9E10) |
CNY 800.00 |