HDAC4 Mouse Monoclonal Antibody [Clone ID: OTI1E12]

Specifications

Product Data
Clone Name	OTI1E12
Applications	WB
Recommend Dilution	WB 1:2000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human HDAC4 (NP_006028) produced in HEK293T cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	118.9 kDa
Gene Name	histone deacetylase 4
Database Link	NP_006028 Entrez Gene 208727 MouseEntrez Gene 363287 RatEntrez Gene 9759 Human UniProt ID P56524
Background	Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008]
Synonyms	AHO3; BDMR; HA6116; HD4; HDAC-4; HDAC-A; HDACA
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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