RSPO3 Mouse Monoclonal Antibody [Clone ID: OTI4G10]

Specifications

Product Data
Clone Name	OTI4G10
Applications	WB
Recommend Dilution	WB 1:500
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 22-272 of human RSPO3 (NP_116173) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	30.7 kDa
Gene Name	R-spondin 3
Database Link	NP_116173 Entrez Gene 72780 MouseEntrez Gene 498997 RatEntrez Gene 84870 Human UniProt ID Q9BXY4
Background	This gene belongs to the R-spondin family. The encoded protein plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis. Genome-wide association studies suggest a correlation of this gene with bone mineral density and risk of fracture. This gene may be involved in tumor development. [provided by RefSeq, Jul 2013]
Synonyms	CRISTIN1; PWTSR; THSD2
Reference Data
Protein Families	Druggable Genome, Secreted Protein

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