TFB1M Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI3G8]

Specifications

Product Data
Clone Name	OTI3G8
Applications	WB
Recommend Dilution	WB 1:2000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 116-346 of human TFB1M (NP_057104) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	39.4 kDa
Gene Name	transcription factor B1, mitochondrial
Database Link	NP_057104 Entrez Gene 308140 RatEntrez Gene 51106 Human UniProt ID Q8WVM0
Background	The protein encoded by this gene is a dimethyltransferase that methylates the conserved stem loop of mitochondrial 12S rRNA. The encoded protein also is part of the basal mitochondrial transcription complex and is necessary for mitochondrial gene expression. The methylation and transcriptional activities of this protein are independent of one another. Variations in this gene may influence the severity of aminoglycoside-induced deafness (AID). [provided by RefSeq, Aug 2010]
Synonyms	CGI-75; CGI75; mtTFB; mtTFB1
Reference Data
Protein Families	Transcription Factors

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