L Kynurenine Hydrolase (KYNU) Mouse Monoclonal Antibody [Clone ID: OTI5E4]

Specifications

Product Data
Clone Name	OTI5E4
Applications	IHC, WB
Recommend Dilution	WB 1:500, IHC 1:150
Reactivity	Human, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 1-216 of human KYNU (NP_001028170) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	34.5 kDa
Gene Name	kynureninase
Database Link	NP_001028170 Entrez Gene 116682 RatEntrez Gene 8942 Human UniProt ID Q16719
Background	Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]
Synonyms	KYNUU
Reference Data
Protein Families	Protease
Protein Pathways	Metabolic pathways, Tryptophan metabolism

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