Kallikrein 8 (KLK8) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI11C3]

Specifications

Product Data
Clone Name	OTI11C3
Applications	IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 33-260 of human KLK8 (NP_009127) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	HRP
Storage Condition	Store at -20°C as received.
Predicted Protein Size	27.9 kDa
Gene Name	kallikrein related peptidase 8
Database Link	NP_009127 Entrez Gene 11202 Human UniProt ID O60259
Background	Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in four transcript variants encoding four different isoforms. The isoforms exhibit distinct patterns of expression that suggest roles in brain plasticity and ovarian cancer. [provided by RefSeq, Jul
Synonyms	HNP; NP; NRPN; PRSS19; TADG14
Reference Data
Protein Families	Druggable Genome, Secreted Protein, Transmembrane

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