Hamartin (TSC1) Mouse Monoclonal Antibody [Clone ID: OTI5A8]

Specifications

Product Data
Clone Name	OTI5A8
Applications	IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 836-1164 of human TSC1 (NP_000359) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	129.6 kDa
Gene Name	tuberous sclerosis 1
Database Link	NP_000359 Entrez Gene 60445 RatEntrez Gene 64930 MouseEntrez Gene 7248 Human UniProt ID Q92574
Background	This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun
Synonyms	LAM; TSC
Reference Data
Protein Pathways	Insulin signaling pathway, mTOR signaling pathway

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