Thymidylate Synthase (TYMS) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI3F1]
CAT#: TA801677AM
TYMS mouse monoclonal antibody,clone 3F1, Biotinylated
Conjugation: Unconjugated HRP
View other "OTI3F1" antibodies (4)
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CNY 3,990.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
Specifications
Product Data | |
Clone Name | OTI3F1 |
Applications | IHC, WB |
Recommend Dilution | WB 1:2000, IHC 1:150 |
Reactivity | Human, Mouse, Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human TYMS (NP_001062) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.5 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Biotin |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 35.5 kDa |
Gene Name | thymidylate synthetase |
Database Link | |
Background | Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase. [provided by RefSeq, Jul 2008] |
Synonyms | HST422; TMS; TS |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Metabolic pathways, One carbon pool by folate, Pyrimidine metabolism |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF801677 | Carrier-free (BSA/glycerol-free) TYMS mouse monoclonal antibody, clone OTI3F1 (formerly 3F1) |
CNY 3,999.00 |
|
TA801677 | TYMS mouse monoclonal antibody, clone OTI3F1 (formerly 3F1) |
CNY 1,999.00 |
|
TA801677BM | TYMS mouse monoclonal antibody,clone 3F1, HRP conjugated |
CNY 3,990.00 |
|
TA801677S | TYMS mouse monoclonal antibody, clone OTI3F1 (formerly 3F1) |
CNY 800.00 |
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