HIF3 alpha (HIF3A) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4C2]

Specifications

Product Data
Clone Name	OTI4C2
Applications	IHC, WB
Recommend Dilution	WB 1:200, IHC 1:150
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 355-669 of human HIF3A (NP_690008) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	72.3 kDa
Gene Name	hypoxia inducible factor 3 alpha subunit
Database Link	NP_690008 Entrez Gene 64344 Human UniProt ID Q9Y2N7
Background	The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011]
Synonyms	bHLHe17; HIF-3A; HIF3-alpha-1; IPAS; MOP7; PASD7
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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