CNOT4 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2F10]

Specifications

Product Data
Clone Name	OTI2F10
Applications	WB
Recommend Dilution	WB 1:2000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 190-455 of human CNOT4 (NP_037448) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	70.2 kDa
Gene Name	CCR4-NOT transcription complex subunit 4
Database Link	NP_037448 Entrez Gene 53621 MouseEntrez Gene 312227 RatEntrez Gene 4850 Human UniProt ID O95628
Background	The protein encoded by this gene is a subunit of the CCR4-NOT complex, a global transcriptional regulator. The encoded protein interacts with CNOT1 and has E3 ubiquitin ligase activity. Several transcript variants encoding different isoforms have been found for this gene.
Synonyms	CLONE243; NOT4; NOT4H
Reference Data
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	RNA degradation

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