Asialoglycoprotein Receptor 1 (ASGR1) Rabbit Monoclonal Antibody [Clone ID: OTIR1H6]

Specifications

Product Data
Clone Name	OTIR1H6
Applications	WB
Recommend Dilution	WB1:500
Reactivity	Human
Host	Rabbit
Clonality	Monoclonal
Immunogen	Synthetic peptide 200-260aa
Formulation	PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1mg/ml
Purification	Purified from cell culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws.
Predicted Protein Size	40 kDa
Gene Name	asialoglycoprotein receptor 1
Database Link	Entrez Gene 432 Human UniProt ID P07306
Background	This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Reference Data

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