TXNDC5 Rabbit Monoclonal Antibody [Clone ID: OTIR4D8]

Specifications

Product Data
Clone Name	OTIR4D8
Applications	SISCAPA
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Monoclonal
Immunogen	Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human TXNDC5 (NP_110437). The exact sequence is proprietary.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	Lot dependent; please refer to CoA along with shipment
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	47.6 kDa
Gene Name	thioredoxin domain containing 5
Database Link	NP_110437 Entrez Gene 105245 MouseEntrez Gene 81567 Human UniProt ID Q8NBS9
Background	This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal endoplasmic reticulum (ER)-signal sequence, three catalytically active thioredoxin domains and a C-terminal ER-retention sequence. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S5 gene. [provided by RefSeq, Dec 2016]
Synonyms	ENDOPDI; ERP46; HCC-2; HCC2; PDIA15; STRF8; UNQ364
Reference Data
Protein Families	Druggable Genome

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