PIK3C2B Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2G3]

CAT#: TA506011AM

PIK3C2B mouse monoclonal antibody, clone OTI2G3 (formerly 2G3), Biotinylated

Conjugation: Unconjugated Biotin HRP



  View other "OTI2G3" antibodies (4)

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CNY 3,990.00


货期*
2周

规格
    • 100 ul

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经常一起买 (3)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
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Recombinant protein of human phosphoinositide-3-kinase, class 2, beta polypeptide (PIK3C2B), 20 µg
    • 20 ug

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Transient overexpression lysate of phosphoinositide-3-kinase, class 2, beta polypeptide (PIK3C2B)
    • 100 ug

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Specifications

Product Data
Clone Name OTI2G3
Applications IF, IHC, WB
Recommend Dilution WB 1:2000~4000, IHC 1:150, IF 1:100
Reactivity Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human PIK3C2B(NP_002637) produced in HEK293T cell.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Biotin
Storage Condition Store at -20°C as received.
Gene Name phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
Background The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is sensitive to low nanomolar levels of the inhibitor wortmanin. The C2 domain of this protein was shown to bind phospholipids but not Ca2+, which suggests that this enzyme may function in a calcium-independent manner. [provided by RefSeq, Jul 2008]
Synonyms C2-PI3K
Reference Data
Protein Families Druggable Genome
Protein Pathways Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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