ERp57 (PDIA3) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI3H5]

Specifications

Product Data
Clone Name	OTI3H5
Applications	IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 140-505 of human PDIA3(NP_005304) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	HRP
Storage Condition	Store at -20°C as received.
Predicted Protein Size	54.2 kDa
Gene Name	protein disulfide isomerase family A member 3
Database Link	NP_005304 Entrez Gene 14827 MouseEntrez Gene 29468 RatEntrez Gene 2923 Human UniProt ID P30101
Background	This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. [provided by RefSeq, Jul 2008]
Synonyms	ER60; ERp57; ERp60; ERp61; GRP57; GRP58; HEL-S-93n; HEL-S-269; HsT17083; P58; PI-PLC
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Antigen processing and presentation

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