ATRIP Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI5E7]

Specifications

Product Data
Clone Name	OTI5E7
Applications	FC, IF, IHC, WB
Recommend Dilution	WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100
Reactivity	Human, Dog
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 42-309 of human ATRIP(NP_569055) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	85.7 kDa
Gene Name	ATR interacting protein
Database Link	NP_569055 Entrez Gene 608504 DogEntrez Gene 84126 Human UniProt ID Q8WXE1
Background	The product of this gene is an essential component of the DNA damage checkpoint, and binds to single-stranded DNA coated with replication protein A that accumulates at sites of DNA damage. The encoded protein interacts with the ataxia telangiectasia and Rad3 related protein, a checkpoint kinase, resulting in accumulation of the kinase at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Synonyms	DKFZp762J2115; FLJ12343; MGC20625; MGC21482; MGC26740
Reference Data

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