SIRT5 Mouse Monoclonal Antibody [Clone ID: OTI 2E12]

Specifications

Product Data
Clone Name	OTI 2E12
Applications	FC, IF, WB
Recommend Dilution	WB 1:500, FLOW 1:100, IF: 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human SIRT5 (NP_036373) produced in HEK293T cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.57 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	sirtuin 5
Database Link	NP_036373 Entrez Gene 68346 MouseEntrez Gene 306840 RatEntrez Gene 23408 Human UniProt ID Q9NXA8
Background	This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2010]
Synonyms	SIR2L5
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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