ALDH1A3 Mouse Monoclonal Antibody [Clone ID: OTI4B6]

Specifications

Product Data
Clone Name	OTI4B6
Applications	FC, IHC, WB
Recommend Dilution	WB 1:200, IHC 1:150, FLOW 1:100
Reactivity	Human, Dog, Monkey, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 1-100 and 413-512 of human ALDH1A3 (NP_000648) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	55.9 kDa
Gene Name	aldehyde dehydrogenase 1 family member A3
Database Link	NP_000684 Entrez Gene 100856346 DogEntrez Gene 694231 MonkeyEntrez Gene 220 Human UniProt ID P47895
Background	Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The enzyme encoded by this gene uses retinal as a substrate, either in a free or cellular retinol-binding protein form. [provided by RefSeq, Jul 2008]
Synonyms	ALDH1A6; ALDH6; MCOP8; RALDH3
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Drug metabolism - cytochrome P450, Glycolysis / Gluconeogenesis, Histidine metabolism, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Phenylalanine metabolism, Tyrosine metabolism

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