Cytoplasmic dynein 1 light intermediate chain 1 (DYNC1LI1) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2E8]

Specifications

Product Data
Clone Name	OTI2E8
Applications	FC, IF, WB
Recommend Dilution	WB 1:500, IF 1:100, FLOW 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human DYNC1LI1 (NP_057225) produced in HEK293T cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	56.4 kDa
Gene Name	dynein cytoplasmic 1 light intermediate chain 1
Database Link	NP_057225 Entrez Gene 235661 MouseEntrez Gene 252902 RatEntrez Gene 51143 Human UniProt ID Q9Y6G9
Background	Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress throuh the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores.
Synonyms	DLC-A; DNCLI1; LIC1
Reference Data

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