HIPPI (IFT57) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI5B6]

CAT#: TA500906AM

Anti-IFT57 (HIPPI) mouse monoclonal antibody, clone OTI5B6 (formerly 5B6), Biotinylated

Conjugation: Unconjugated Biotin HRP



  View other "OTI5B6" antibodies (4)

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CNY 3,990.00


货期*
2周

规格
    • 100 ul

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Recombinant protein of human intraflagellar transport 57 homolog (Chlamydomonas) (IFT57), 20 µg
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Transient overexpression lysate of intraflagellar transport 57 homolog (Chlamydomonas) (IFT57)
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Specifications

Product Data
Clone Name OTI5B6
Applications IHC, WB
Recommend Dilution WB 1:500, IHC 1:50
Reactivity Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human IFT57 (NP_060480) produced in HEK293T cell.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Biotin
Storage Condition Store at -20°C as received.
Predicted Protein Size 48.9 kDa
Gene Name intraflagellar transport 57
Background Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator.
Synonyms ESRRBL1; HIPPI; MHS4R2
Reference Data
Protein Families Druggable Genome
Protein Pathways Huntington's disease
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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