TRPM4 Mouse Monoclonal Antibody [Clone ID: OTI3C4]

CAT#: TA500370S

Anti-TRPM4 mouse monoclonal antibody, clone OTI3C4 (formerly 3C4)

Size: 30 ul 100 ul



  View other "OTI3C4" antibodies (4)

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【特别福利】购一抗正装产品(≥50ul或≥50ug),免费领10ul抗体试用装

CNY 800.00


货期*
现货

规格
    • 30 ul

Product images

经常一起买 (3)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

CNY 300.00
CNY 1,430.00


Recombinant protein of human transient receptor potential cation channel, subfamily M, member 4 (TRPM4), 20 µg
    • 20 ug

CNY 2,900.00
CNY 6,650.00


Transient overexpression lysate of transient receptor potential cation channel, subfamily M, member 4 (TRPM4)
    • 100 ug

CNY 4,840.00

Specifications

Product Data
Clone Name OTI3C4
Applications WB
Recommend Dilution WB 1:2000
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Full-length protein expressed in 293T cell transfected with human TRPM4 expression vector
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1.2 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 134.3 kDa
Gene Name transient receptor potential cation channel subfamily M member 4
Background Calcium-activated non selective (CAN) cation channel that mediates membrane depolarization. While it is activated by increase in intracellular Ca(2+), it is impermeable to it. Mediates transport of monovalent cations (Na(+) > K(+) > Cs(+) > Li(+)), leading to depolarize the membrane. It thereby plays a central role in cadiomyocytes, neurons from entorhinal cortex, dorsal root and vomeronasal neurons, endocrine pancreas cells, kidney epithelial cells, cochlea hair cells etc. Participates in T-cell activation by modulating Ca(2+) oscillations after T lymphocyte activation, which is required for NFAT-dependent IL2 production. Involved in myogenic constriction of cerebral arteries. Controls insulin secretion in pancreatic beta-cells. May also be involved in pacemaking or could cause irregular electrical activity under conditions of Ca(2+) overload
Synonyms hTRPM4; LTrpC4; PFHB1B; TRPM4B
Reference Data
Protein Families Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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