Cd3e Hamster Monoclonal Antibody [Clone ID: 145-2C11]

Specifications

Product Data
Clone Name	145-2C11
Applications	FC, IF, IHC, IP, WB
Host	Hamster
Clonality	Monoclonal
Immunogen	H-2Kb - specific mouse cytotoxic T lymphocyte clone BM10-37.
Specificity	CD3
Formulation	Phosphate buffered saline containing 0.09% Sodium Azide (NaN3) Label: ALEXA FLUOR® 488,ALEXA FLUOR® 647,Amethyst Blue,Amethyst Orange,Biotin,FITC,Pacific Blue®,Purified,RPE,RPE-CY5,RPE-CY5.5,RPE-CY7 State: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant Purified IgG - liquid
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	+4°C, -20°C if preferred
Gene Name	CD3 antigen, epsilon polypeptide
Database Link	UniProt ID P22646
Background	Hamster anti Mouse CD3 antibody, clone 145-2C11 detects CD3 epsilon (CD3ε), a ~20 kDa transmembrane protein also known as CD3 or T3. CD3ε is a member of the CD3 complex which consists of four subunits, gamma, delta, epsilon and zeta, and these are associated to the T cell receptor (TCR). TCR plays a critical role in T cell development and function, and is responsible for ligand recognition. It interacts non-covalently with the CD3 dimers delta/epsilon, gamma/epsilon and zeta/zeta which transduce signals from the TCR into the cell.CD3ε is primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation.Hamster anti Mouse CD3 antibody, clone 145-2C11 is useful for in vitro blocking and activation assays, as well as apoptosis induction and in vitro T cell depletions.
Synonyms	CD3-epsilon; FLJ18683; T3E; TCRE
Reference Data

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