Phospho-IRF3 Rabbit Polyclonal Antibody
CNY 7,740.00
货期*
5周
规格
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Specifications
Product Data | |
Applications | WB |
Recommend Dilution | WB,1:2000 - 1:24000 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | A synthetic phosphorylated peptide around S396 of human IRF3 (NP_001562.1). |
Formulation | Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20℃. Avoid freeze / thaw cycles. |
Predicted Protein Size | 47kDa - Observed MW: 45-55kDa |
Gene Name | interferon regulatory factor 3 |
Database Link | |
Background | This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses. Mutations in this gene are associated with Encephalopathy, acute, infection-induced, herpes-specific, 7. |
Synonyms | IIAE7 |
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