Phospho-BAD Rabbit Polyclonal Antibody
CNY 7,740.00
货期*
5周
规格
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Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | WB,1:2000 - 1:8000 IHC-P,1:500 - 1:1000 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | A phospho specific peptide corresponding to residues surrounding S112 of human Bad. |
Formulation | Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20℃. Avoid freeze / thaw cycles. |
Predicted Protein Size | 18kDa - Observed MW: 23kDa |
Gene Name | BCL2 associated agonist of cell death |
Database Link | |
Background | The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL (B-cell lymphoma-extra large) and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. |
Synonyms | BBC2; BCL2L8 |
Reference Data |
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