Phospho-HDAC4 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB,1:1000 - 1:5000
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic phosphorylated peptide around S632 of human Phospho-HDAC4-S632 (NP_006028.2).
Formulation	Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size	119kDa - Observed MW: 100kDa/120kDa
Gene Name	histone deacetylase 4
Database Link	Entrez Gene 9759 Human UniProt ID P56524
Background	Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
Synonyms	AHO3; BDMR; HA6116; HD4; HDAC-4; HDAC-A; HDACA; NEDCHF; NEDCHID
Reference Data

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