CALCA Monoclonal Antibody [Clone ID: 18C4.B4.C2]

Specifications

Product Data
Clone Name	18C4.B4.C2
Applications	ELISA, WB
Recommend Dilution	WB: 1:1,000 - 1:2,000 ELISA: User Optimized
Reactivity	Human
Clonality	Monoclonal
Immunogen	Procalcitonin Antibody was produced in mice prepared by repeated immunizations with full-length recombinant human Procalcitonin protein.
Specificity	Anti-Procalcitonin Antibody was purified from concentrated tissue culture supernate by Protein A chromatography. This antibody is specific for human Procalcitonin. Cross-reactivity with Procalcitonin from other sources has not been determined.
Formulation	0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Concentration	1.0 mg/ml - lot specific
Conjugation	Unconjugated
Storage Condition	Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Database Link	UniProt ID P06881
Background	Anti-Procalcitonin antibody detects human Procalcitonin. Procalcitonin is a peptide hormone mainly produced by the C cells of the thyroid and certain endocrine cells of the lung. Under normal expression conditions, procalcitonin is immediately cleaved into three specific fragments, a N terminal residue, calcitonin and katacalcin. Levels of unprocessed procalcitonin rise significantly after bacterial infection, trauma or shock. This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms	mouse anti-procalcitonin antibody, calcitonin isoform CT preproprotein, calcitonin-related polypeptide alpha, CT, KC, CGRP, CALC1, CGRP1, CGRP-I
Note	Anti-Procalcitonin [18C4.B4.C2] antibody was tested by ELISA and Western Blot. Specific conditions for reactivity should be optimized by the end user.
Reference Data

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