IL3RA Polyclonal Antibody [Clone ID: 6H6]

Specifications

Product Data
Clone Name	6H6
Applications	FC
Recommend Dilution	Purified antibody is conjugated with activated Peridinin-Chlorophyll Protein (PerCP) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Reactivity	Human
Clonality	Polyclonal
Immunogen	IL3 receptor alpha chain expressed on the surface of transiently transfected COS cells
Specificity	The mouse monoclonal antibody 6H6 recognizes an extracellular epitope of CD123 (interleukin 3 receptor alpha), a 60-70 kDa transmembrane protein expressed by myeloid precursors, megakaryocytes, macrophages, dendritic cells, mast cells, basophils, and some B cells. This antibody does not inhibit IL-3 binding to its receptor.
Formulation	Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide Format: PerCP Label: Purified antibody is conjugated with activated Peridinin-Chlorophyll Protein (PerCP) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Concentration	lot specific
Purification	*Sun Q, Woodcock JM, Rapoport A, Stomski FC, Korpelainen EI, Bagley CJ, Goodall GJ, Smith WB, Gamble JR, Vadas MA, Lopez AF: Monoclonal antibody 7G3 recognizes the N-terminal domain of the human interleukin-3 (IL-3) receptor alpha-chain and functions as a specific IL-3 receptor antagonist. Blood. 1996 Jan 1;87(1):83-92., URL: https://pubmed.ncbi.nlm.nih.gov/8547680/,*Martín-Gayo E, Sierra-Filardi E, Corbí AL, Toribio ML: Plasmacytoid dendritic cells resident in human thymus drive natural Treg cell development. Blood. 2010 Jul 1;115(26):5366-75., URL: http://www.ncbi.nlm.nih.gov/pubmed/20357241 ,*Herling M, Teitell MA, Shen RR, Medeiros LJ, Jones D: TCL1 expression in plasmacytoid dendritic cells (DC2s) and the related CD4+ CD56+ blastic tumors of skin. Blood. 2003 Jun 15;101(12):5007-9., URL: http://www.ncbi.nlm.nih.gov/pubmed/12576313
Conjugation	Unconjugated
Storage Condition	Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Gene Name	interleukin 3 receptor subunit alpha
Database Link	Entrez Gene 3563 Human UniProt ID P26951
Synonyms	IL3RA, MGC34174, hIL-3Ra
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.