EIF4G1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500~1:1000
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic peptide corresponding to residues in Human EIF4G1 around the phosphorylation site of S1148.
Specificity	EIF4G1 (phospho-S1148) polyclonal antibody detects endogenous levels of EIF4G1 protein around the phosphorylation site of S1148.
Formulation	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration	1mg/ml
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size	~ 175 kDa
Gene Name	eukaryotic translation initiation factor 4 gamma 1
Database Link	Entrez Gene 1981 Human UniProt ID Q04637
Background	The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. The eukaryotic initiation complex eIF4F exists in vitro as a trimeric complex of eIF4G, eIF4E, and eIF4A. Together, the complex allows ribosome binding to mRNA by inducing the unwinding of mRNA secondary structures. eIF4E binds to the mRNA “cap” during an early step in the initiation of protein synthesis. eIF4A acts as an ATP-dependent RNA helicase. eIF4G acts as a bridge between eIF4E, eIF4A, and the eIF3 complex .
Synonyms	eIF-4-gamma 1; eIF-4G 1; eIF-4G1; EIF4F; EIF4G; EIF4G1; EIF4GI; Eukaryotic translation initiation factor 4 gamma 1; p220
Note	For research use only, not for use in diagnostic procedure.
Reference Data

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