SRC3 (NCOA3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500~1:1000 IHC: 1:50~1:200
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide, corresponding to amino acids 558-600 of Human NCoA-3.
Specificity	NCoA-3 (S587) polyclonal antibody detects endogenous levels of NCoA-3 protein.
Formulation	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration	1mg/ml
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size	~ 155 kDa
Gene Name	nuclear receptor coactivator 3
Database Link	Entrez Gene 8202 Human UniProt ID Q9Y6Q9
Background	Several related transcriptional coactivators and corepressors have been described that work in concert with the steroid receptor family to either induce or repress transcription from hormone-responsive elements. This family includes GRIP1 (for GR interacting protein 1), also designated NCoA-2 or TIF-2; SRC-1 (for steroid receptor coactivator-1), also designated NCoA-1; and NCoA-3, also designated RAC3, ACTR, AIB-1 (for amplified in breast cancer) and p/CIP (for p300/CBP/co-integrator protein), which displays elevated expression in estrogen receptor positive ovarian and breast cancers and is required for the transcriptional activation of p300/CBP-dependent transcription factors.
Synonyms	ACTR; AIB-1; AIB1; Amplified in breast cancer 1 protein; bHLHe42; BHLHE42; CBP-interacting protein; Class E basic helix-loop-helix protein 42; EC=2.3.1.48; NCoA-3; NCOA3; Nuclear receptor coactivator 3; pCIP; RAC-3; RAC3; Receptor-associated coactivator 3; SRC-3; Steroid receptor coactivator protein 3; Thyroid hormone receptor activator molecule 1; TRAM-1; TRAM1
Note	For research use only, not for use in diagnostic procedure.
Reference Data

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