CD51 (ITGAV) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500~1:1000 IHC: 1:50~1:200
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide, corresponding to amino acids 771-820 of Human Integrin αV.
Specificity	Integrin αV (P804) polyclonal antibody detects endogenous levels of Integrin αV protein.
Formulation	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration	1mg/ml
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size	~ 116 kDa
Gene Name	integrin subunit alpha V
Database Link	Entrez Gene 3685 Human UniProt ID P06756
Background	The integrin family contains at least 18 α and 8 β subunits that form 24 known integrins with distinct tissue distribution and overlaping ligand specificities. Integrins not only transmit signals to cells in response to the extracellular environment (outside-in signaling), but also sense intracellular cues to alter their interaction with extracellular environment (inside-out signaling).Several αV subfamily members, including αVβ3, αVβ5, αVβ1, are highly expressed in active endothelial cells and cancer cells where they play a critical role in angiogenesis and tumor metastasis.
Synonyms	CD51; Integrin alpha-V; Integrin alpha-V heavy chain; Integrin alpha-V light chain; ITGAV; MSK8; Vitronectin receptor subunit alpha; VNRA
Note	For research use only, not for use in diagnostic procedure.
Reference Data

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