DNAL1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500~1:1000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide, corresponding to amino acids 128-184 of Human DNAL1.
Specificity	DNAL1 (N161) polyclonal antibody detects endogenous levels of DNAL1 protein.
Formulation	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration	1mg/ml
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size	~ 22 kDa
Gene Name	dynein axonemal light chain 1
Database Link	Entrez Gene 83544 Human UniProt ID Q4LDG9
Background	Dyneins are multi-subunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal dynein heavy, intermediate, light and light-intermediate chains are all components of minus end-directed motors. Dynein complexes transport cellular cargos toward the central region of the cell. Containing one to three non-identical heavy chains, axonemal dynein motors cause a sliding of microtubules in the axonemes of cilia and flagella in a mechanism necessary for cilia movement and cell propulsion. DNAL1 (dynein light chain 1, axonemal), also known as MGC12435 or C14orf168, is a 190 amino acid member of the dynein light chain LC1-type protein family. Containing four leucine-rich repeats, DNAL1 interacts directly with DNAH5. DNAL1 is expressed in testis and other tissues carrying motile cilia.
Synonyms	axonemal; C14orf168; Dynein light chain 1
Note	For research use only, not for use in diagnostic procedure.
Reference Data

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