Apolipoprotein B (APOB) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500~1:1000
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant APOB protein, corresponding to amino acids 97-526 of Human APOB.
Specificity	APOB polyclonal antibody detects endogenous levels of APOB protein.
Formulation	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration	1mg/ml
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size	~ 516 kDa
Gene Name	apolipoprotein B
Database Link	Entrez Gene 338 Human UniProt ID P04114
Background	Post-transcriptional editing of apolipoprotein B (apoB) mRNA is regulated by APOBEC1 (also designated human (or rat) small intestinal apolipoprotein B mRNA editing protein, HEPR, or REPR) in hepatic cells to achieve a steady state proportion of edited and unedited RNA molecules. Two forms of apoB are known to circulate in the plasma of mammals. apoB-100 is a protein primarily synthesized in the liver as a structural component of very-low-density lipoprotein particles. A truncated form of apoB-100, apoB-48, is synthesized in the small intestine and contains the amino-terminal 2,152 amino acids of the larger protein. This organ-specific partitioning of apoB production is the result of RNA editing of a common apoB gene.
Synonyms	Apo B-100; Apolipoprotein B-100
Note	For research use only, not for use in diagnostic procedure.
Reference Data

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