GGPS1 Rabbit Polyclonal Antibody

CAT#: TA392697

GGPS1 polyclonal antibody

Size: 25 ul 100 ul



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CNY 1,999.00

CNY 3,350.00


货期*
2周

规格
    • 100 ul

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Specifications

Product Data
Applications WB
Recommend Dilution WB: 1:500~1:1000 IHC: 1:50~1:200
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Recombinant fragment corresponding to a region within amino acids 1-295 of Human GGPS1.
Specificity GGPS1 polyclonal antibody detects endogenous levels of GGPS1 protein.
Formulation Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration 1mg/ml
Conjugation Unconjugated
Storage Condition Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size ~ 35 kDa
Gene Name geranylgeranyl diphosphate synthase 1
Background GGPS1 (geranylgeranyl diphosphate synthase 1), also known as GGPPS, GGPPSase (geranylgeranyl pyrophosphate synthetase) or GGPPS1, is a member of the FPP/GGPP synthetase family of trans-prenyltransferases. Predominantly expressed in testis, heart and skeletal muscle, GGPS1 localizes to the cytoplasm and catalyzes the formation of geranylgeranyl pyrophosphate (GGPP), a precursor of geranylgeranylated proteins and carotenoids. GGPP is a major isoprenoid responsible for the C20-prenylation of proteins and the regulation of the nuclear hormone receptor LXRå. More specifically, GGPS1 functions as an oligomeric molecule and mediates the condensation of farnesyl diphosphate (FPP) with isopentenyl diphosphate to yield GGPP. GGPS1 contains five amino acid motifs that are conserved in trans-prenyltransferases and three potential N-glycosylation sites.
Synonyms (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyltranstransferase; Geranylgeranyl diphosphate synthase; Geranylgeranyl pyrophosphate synthase; Geranyltranstransferase; GGPPSase; GGPP synthase; GGPS1
Note For research use only, not for use in diagnostic procedure.
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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