AK6 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500~1:1000 IHC: 1:50~1:200 IP: 1:10~1:100
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide, corresponding to the N-terminual of Human AK6.
Specificity	AK6 (G35) polyclonal antibody detects endogenous levels of AK6 protein.
Formulation	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration	1mg/ml
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size	~ 20 kDa
Gene Name	adenylate kinase 6
Database Link	Entrez Gene 102157402 Human UniProt ID Q9Y3D8
Background	TAF9(AK6) functions as a component of the DNA-binding general transcription factor complex TFIID and the regulatory transcription complex SAGA. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription. SAGA influences RNA polymerase II transcriptional activity through different activities such as TBP interaction (SPT3 and SPT8) and promoter selectivity, interaction with transcription activators (GCN5, ADA2, ADA3, and TRA1), and chromatin modification through histone acetylation (GCN5).
Synonyms	AD-004; Adenylate kinase isoenzyme 6; Adrenal gland protein AD-004; AK/ATPase; AK6; CGI-137; CINAP; Coilin-interacting nuclear ATPase protein; Dual activity adenylate kinase/ATPase; hCINAP
Note	For research use only, not for use in diagnostic procedure.
Reference Data

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