Beclin 1 (BECN1) Rabbit Polyclonal Antibody

CAT#: TA392590S

Beclin 1 polyclonal antibody

Size: 25 ul 100 ul



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CNY 800.00


货期*
2周

规格
    • 25 ul

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经常一起买 (1)
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Specifications

Product Data
Applications IF, IHC, WB
Recommend Dilution WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide, corresponding to Human Beclin 1.
Specificity Beclin 1 polyclonal antibody detects endogenous levels of Beclin 1 protein.
Formulation Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration 1mg/ml
Conjugation Unconjugated
Storage Condition Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size ~ 60 kDa
Gene Name beclin 1
Background BECN1 (beclin 1) is a coiled-coil protein that has been implicated as an inhibitor of tumorigenesis. BECN1, which associates with Bcl-2, plays a significant role in autophagy. Autophagy is the degradation of cellular proteins in the lysosomes, and when this pathway is suppressed, cell growth is deregulated. Autophagy is controlled by the same signal transduction pathway that induces the phosphorylation of the ribosomal protein S6, and both are mediated via amino acids. BECN1 expression in various carcinoma cell lines, such as MCF7, is low, whereas it is ubiquitously expressed in normal breast tissue.
Synonyms APG6; ATG 6; ATG6; ATG6 autophagy related 6 homolog; Bcl-2-interacting protein beclin; Beclin-1; Beclin1; Beclin 1 (coiled coil moesin like BCL2 interacting protein); Beclin 1 autophagy related; BECN 1; BECN1; Coiled-coil myosin-like BCL2-interacting protein; Coiled coil myosin like BCL2 interacting protein; GT197; Protein GT197 antibod
Note For research use only, not for use in diagnostic procedure.
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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