LAMP1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:1000~1:2000
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide, corresponding to Human CD107a/LAMP1.
Specificity	CD107a/LAMP1 polyclonal antibody detects endogenous levels of CD107a/LAMP1 protein.
Formulation	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Concentration	1mg/ml
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size	~ 95 kDa
Gene Name	lysosomal associated membrane protein 1
Database Link	Entrez Gene 3916 Human UniProt ID P11279
Background	Lysosome-associated membrane protein 1 and 2 (LAMP1 and LAMP2) are two abundant lysosomal membrane proteins. Both are transmembrane proteins and are heavily glycosylated at the amino-terminal luminal side of the lysosomal inner leaflet, which protects the proteins from proteolysis. The carboxy terminus of LAMP1 is exposed to the cytoplasm and contains a tyrosine sorting motif that targets LAMP to lysosomal membranes. LAMP1 and LAMP2 are 37% homologous in their protein sequences. Both LAMP1 and LAMP2 are involved in regulating lysosomal motility during lysosome-phagosome fusion and cholesterol trafficking.
Synonyms	CD107 antigen-like family member A; CD107a; LAMP-1; LAMP1; Lysosome-associated membrane glycoprotein 1; Lysosome-associated membrane protein 1
Note	For research use only, not for use in diagnostic procedure.
Reference Data

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