Anti-IL17RA antibody(DM125), Rabbit mAb

Specifications

Product Data
Clone Name	DM125
Applications	FC
Recommend Dilution	Flow Cyt 1:100
Reactivity	Human
Host	Rabbit
Clonality	Monoclonal
Formulation	1XPBS
Concentration	Lot specific
Purification	Purified from cell culture supernatant by affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Background	Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.
Synonyms	CD217,CDw217,IL-17RA,IL17R,CANDF5,hIL-17R
Reference Data

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