(pSer/Thr) Mouse Antibody [Clone ID: M380A/M380B]
CAT#: TA389185
Anti-Anti-Phosphoserine/threonine Antibody
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CNY 4,069.00
货期*
5周
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Specifications
Product Data | |
Clone Name | M380A/M380B |
Applications | ICC, IP, WB |
Recommend Dilution | WB: 1:500 ICC: 1:50 |
Reactivity | Human, Rat, Mouse |
Host | Mouse |
Immunogen | PM3801 Phosphoserine/threonine is a mix of two clones: Clone M380A was generated from a phosphothreonine synthetic peptide (coupled to carrier protein) and Clone M380B was generated.from a phosphoserine synthetic peptide (coupled to carrier protein). |
Specificity | The antibody detects many serine or threonine phosphorylated proteins by western blot, immunocytochemistry, and ELISA. |
Formulation | PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol |
Concentration | lot specific |
Purification | Protein A Purified |
Conjugation | Unconjugated |
Storage Condition | Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C. |
Background | Phosphorylation of specific serine or threonine residues is an important post-translational modification for regulating the activity of most proteins. Stimulation of a variety of cell signaling pathways activates the receptor and non-receptor ser/thr kinases that mediate these protein modifications. Antibodies that can detect phosphoserine or phosphothreonine residues are excellent tools for characterizing changes in the post-translational state of a broad range of phosphorylated proteins. Immunoprecipitation of proteins of interest followed by detection of phosphoserine or phosphothreonine using anti-phosphoserine antibody is commonly used to correlate changes in phosphorylation state with alterations in protein activity. |
Note | Protein G purified tissue culture supernatant. |
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