NeuN (RBFOX3) Mouse Monoclonal Antibody [Clone ID: 1B7]

Specifications

Product Data
Clone Name	1B7
Applications	ICC, IHC, WB
Recommend Dilution	WB: 1:2000 WB Brain: 1:2000 ICC: 1:200-1:1000
Reactivity	Bovine, Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant protein taken from the N-terminus of human FOX3 expressed in and purified from E. Coli.
Specificity	Specific for endogenous levels of the ~46/48 kDa FOX3 protein doublet.
Formulation	PBS + 50% glycerol and 5 mm NaN3
Concentration	lot specific
Purification	Protein G Purified
Conjugation	Unconjugated
Storage Condition	Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
Predicted Protein Size	46/48
Gene Name	RNA binding protein, fox-1 homolog 3
Database Link	Entrez Gene 146713 Human UniProt ID A6NFN3
Background	FOX3, also known as NeuN and hexaribonucleotide binding protein 3, is a neuron-specific RNA binding nuclear protein involved in the regulation of pre-mRNA alternative splicing (Kim et al., 2009). FOX3 dependent alternative splicing of Numb has recently been shown to play an important role in the progression of neuronal differentiation during vertebrate development (Kim et al., 2013).
Synonyms	Fox-3; Hrnbp3; NeuN; Neun; Neuna60; RGD1560070
Note	Protein G purified culture supernatant.
Reference Data

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