ARRDC3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Recommended dilution: WB:1:500-1:5000
Reactivity	Mouse, Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant Human Arrestin domain-containing protein 3 protein (1-270AA)
Formulation	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Concentration	lot specific
Purification	>95%, Protein G purified
Conjugation	Unconjugated
Storage Condition	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Database Link	UniProt ID Q96B67
Background	Adapter protein that plays a role in regulating cell-surface expression of adrenergic receptors and probably also other G protein-coupled receptors (PubMed:20559325, PubMed:21982743, PubMed:23208550). Plays a role in NEDD4-mediated ubiquitination and endocytosis af activated ADRB2 and subsequent ADRB2 degradation (PubMed:20559325, PubMed:23208550). May recruit NEDD4 to ADRB2 (PubMed:20559325). Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes (PubMed:23208550).
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.